| Interleukin 32 | |
|---|---|
| Identifiers | |
| Symbol | IL32 |
| Alt. symbols | , NK4, TAIF, TAIFb, TAIFd |
| Entrez | 9235 |
| HUGO | 16830 |
| OMIM | 606001 |
| RefSeq | NM_004221 |
| UniProt | P24001 |
| Other data | |
| Locus | Chr. 16 p13.3 |
Interleukin 32 (IL-32) is a cytokine that can induce cells of the immune system (such as monocytes and macrophages) to secrete tumor necrosis factor-alpha (TNF-α) in addition to chemokines such as IL-8 and MIP-2/CXCL2.[1]
IL-32 can also support osteoclast differentiation but not osteoclast activation by regulating the MAPK/ERK pathway and the actin cytoskeleton. [2]
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